Search results for "Optimal management"
showing 10 items of 27 documents
A practical algorithmic approach to mature aggressive B cell lymphoma diagnosis in the double/triple hit era. Selecting cases, matching clinical bene…
2019
An accurate diagnosis of clinically distinct subgroups of aggressive mature B cell lymphomas is crucial for the choice of proper treatment. Presently, precise recognition of these disorders relies on the combination of morphological, immunophenotypical, and cytogenetic/molecular features. The diagnostic workup in such situations implies the application of costly and time-consuming analyses, which are not always required, since an intensified treatment option is reasonably reserved to fit patients. The Italian Group of Haematopathology proposes herein a practical algorithm for the diagnosis of aggressive mature B cell lymphomas based on a stepwise approach, aimed to select cases deserving mo…
Inguinal hernioplasty improves the quality of life in patients with cirrhosis.
2008
Abstract Background The optimal management of symptomatic inguinal hernia (SIH) in cirrhotics is still undefined. Both hernia and cirrhosis impair quality of life (QOL). The aim of this study was to evaluate QOL by a Short Form-36 (SF-36) questionnaire in cirrhotic patients undergoing inguinal hernioplasty. Methods Thirty-two cirrhotic patients undergoing inguinal hernioplasty were evaluated. They were classified according to Child's class and to the absence or presence of refractory ascites. The SF-36 questionnaire was administered the day before and 6 months after surgery. Global analyses of the 8 domains of SF-36 and of 2 comprehensive indexes of SF-36, Physical Component Summary (PCS) a…
Long-term outcomes with subcutaneous C1-inhibitor replacement therapy for prevention of hereditary angioedema attacks
2019
Background For the prevention of attacks of hereditary angioedema (HAE), the efficacy and safety of subcutaneous human C1-esterase inhibitor (C1-INH[SC]; HAEGARDA, CSL Behring) was established in the 16-week Clinical Study for Optimal Management of Preventing Angioedema with Low-Volume Subcutaneous C1-Inhibitor Replacement Therapy (COMPACT). Objective To assess the long-term safety, occurrence of angioedema attacks, and use of rescue medication with C1-INH(SC). Methods Open-label, randomized, parallel-arm extension of COMPACT across 11 countries. Patients with frequent angioedema attacks, either study treatment-naive or who had completed COMPACT, were randomly assigned (1:1) to 40 IU/kg or …
DE.DU.ENER.T. project: A prototype of a sustainable energy microsystem
2016
The paper presents a prototype of a microsystem for the integration and the optimal management of renewable energy sources in order to attain a reduction of the total energy consumption of a not residential building. The system composed by the building and the prototype is an energy sustainable microsystem and is located in Italy in the city of Valderice. The microsystem has been conceived in the ENPI (European Neighborhood and Partnership Instrument) cross-border cooperation Italy - Tunisia 2007-2013 DE.DU.ENER.T. (Le DEveloppement DUrable dans la production ENERgetique dans le Territoire) research project framework. In the paper the purposes of the DE.DU.ENER.T. project are presented and …
Energy saving in airports by trigeneration. Part II: Short and long term planning for the Malpensa 2000 CHCP plant
2006
With reference to the feasibility analysis for CHCP applications in airports performed in Part I of this work, the optimal strategy for repowering and operation of the Malpensa 2000 CHCP plant is here discussed. The analysis starts from experimental energy demand data, available on hourly basis for an entire operational year. After a description of the CHCP lay-out, the optimal management strategy was determined keeping into account the articulated energy tariff system and the technical characteristics of components. A profit-oriented optimization of the repowering actions to take up to 2010 is presented, based on the expected growth of energy consumption due to the scheduled increases in t…
Innovative algorithms for the management of combined RES-BESS systems
2017
The issue of the optimal management of the available energy resources also at end-user level is getting more and more attention. The paper deals with the definition of innovative algorithms for managing electrical storage systems in hybrid photovoltaic and wind plants, also taking into account different pricing periods and a grid emergency condition in which the Utility can request an injection of power by the end-user. Application examples for explaining the operation of the algorithms are presented.
Robust Multi-Objective Optimal dispatch of Distributed Energy Resources in Micro-Grids
2011
Modern distribution systems are implemented through micro grids: small power networks where generation is close to consumption and ICT supports the coordinated management of the different energy resources. In such systems, the central control unit manages energy dispatch from the different sources according to different criteria (technical, economical and environmental) and takes care of tertiary regulation. Such optimization for the tertiary regulation is performed with a time interval that typically is of 24 hours. This is due to the fact that it is necessary to take into account the charge and discharge cycles of storage systems. On the other hand, such long time leads to large errors in…
Energy efficient operation in smart grids: optimal management of shiftable loads and storage systems
2012
In this paper, the authors analyze the impact of the participation of customers to the sustainable implementation of energy rational strategies in microgrids. The management of shiftable loads is compared to the control of real and reactive storage systems in smart grids. An optimization algorithm is used as analysis tool to assess the impact of such control variables in different conditions. The results clearly indicate that if shiftable loads are of suitable size, they have a more promising as tools to both reduce losses and to flatten the peak load through the HV/MV bus. Many tests have been carried out on a real experimental MV system in the area of Rome Italy.
A systematic review on external ear melanoma
2014
Summary Background External ear melanoma accounts for only 1% of all cutaneous melanomas, and data on its optimal management and prognosis are limited. Aim We aim to review the literature on external ear melanoma to guide surgeons in the treatment of this uncommon and peculiar pathology. Materials and methods A systematic review of English language studies on ear melanoma published from 1993 to 2013 was performed using the PubMed electronic database. Data on epidemiology, oncological treatment (tumor resection and regional lymph nodes management), and reconstruction were extrapolated from selected papers. Results The total number of patients was 858 (30 studies). The helix was the most comm…
18F-FDG PET/TC en infección e inflamación cardiovascular
2021
espanolEn cardiologia nuclear, el diagnostico de infeccion e inflamacion cardiovascular mediante PET/TC con [18F]FDG es de interes creciente, ya que esta tecnica ha mejorado la certeza diagnostica en pacientes con endocarditis infecciosa en protesis valvulares respecto a la ecocardiografia, en pacientes con dispositivos intracardiacos, cuya frecuencia de implantacion va en aumento debido al progresivo envejecimiento de la poblacion, asi como en aquellos con sospecha de vasculitis de grandes vasos. Son situaciones clinicas graves, en las que es necesario establecer lo antes posible el diagnostico correcto y el tratamiento adecuado, pues pueden producir complicaciones severas, alta mortalidad…